<b>REGULATION OF PANCREATIC B-CELL REPLICATION BY GLUCOSE AND SOME OTHER </b><b>SUBSTANCES </b>
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چکیده
منابع مشابه
[Pancreatic B cell function and glucose intolerance in the elderly].
In an attempt to define the pancreatic B cell function in the elderly, we subjected 88 non-obese individuals (aged between 21 and 88) to an oral glucose tolerance test (OGTT), a simple glucagon test (SGT) and OGTT-glucagon test, in which the plasma glucose, insulin and serum C-peptide (CPR) were measured. We investigated heterogeneity in glucose intolerance in the elderly and its relationship t...
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Glucose stimulates rodent and human b-cell replication, but the intracellular signaling mechanisms are poorly understood. Carbohydrate response element-binding protein (ChREBP) is a lipogenic glucose-sensing transcription factor with unknown functions in pancreatic b-cells. We tested the hypothesis that ChREBP is required for glucose-stimulated b-cell proliferation. The relative expression of C...
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38. Islam, M. S., Larsson, 0. and Berggren, P.-0. (1993) Science 262,584-585 39. Ammala, C., Larsson, O., Berggren, P.-O., Bokvist, K., Juntti-Rerggren, I,., Kindmark, H. and Rorsman, P. (1991) Nature (London) 353,849-852 40. Rerggren, P.-0.. Rorsman, P., Efendic, S.. Ostenson, C.-G., Flatt, P. R., Nilsson, T., Arkhammar, P. and Juntti-Rerggren, I,. (1992) in Nutrient regulation of insulin secr...
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Introduction Randle’s original idea of a signal function of fuel metabolism for the initiation of insulin secretion by glucose is now generally accepted (for review see [ 13); in the pancreatic B-cell glucose is both a fuel and, at millimolar concentrations, a physiological stimulus for insulin secretion and insulin biosynthesis. The device in the pancreatic B-cell, which translates changes in ...
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ژورنال
عنوان ژورنال: Biomedical Research
سال: 1982
ISSN: 0388-6107,1880-313X
DOI: 10.2220/biomedres.3.688